1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride
1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane hydrochloride (1:1)
CAS: 223251-25-0
Molecular Formula: C15H23Cl2NO
1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride - Names and Identifiers
1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride - Physico-chemical Properties
| Molecular Formula | C15H23Cl2NO |
| Molar Mass | 304.26 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Use | This product is for scientific research only and shall not be used for other purposes. |
1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride - Risk and Safety
| HS Code | 29339900 |
1-[2-[4-(ChloroMethyl)phenoxy]ethyl]hexahydro-1H-azepine hydrochloride - Introduction
1-{2-[4-(Chloromethyl) phenyl] ethyl}azepane hydrochloride (1:1), also known as 1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane hydrochloride (1:1) is an organic compound. Its chemical structure contains benzene ring, epoxy, ethoxy and chlorine groups and other functional groups.
Nature:
-Appearance: White crystal or crystalline powder.
-Solubility: Soluble in water and some organic solvents, such as ethanol and dimethyl sulfoxide.
-Melting Point: about 110-113 ℃.
Use:
-Drug synthesis: 1-{2-[4-(Chloromethyl) phenyl] ethyl}azepane hydrochloride (1:1) is a compound intermediate, commonly used in the preparation of drugs and bioactive molecules.
-Chemical research: The compound can be used in organic synthesis reactions, such as etherification reactions and alkylation reactions.
Method:
A preparation method is to react 4-(2-chloromethyl) phenol with azepane ring under the catalysis of linear sulfuric acid to generate 4-(2-sulfoxyethoxy) benzyl-2-chlorotoluene and subsequent acidification with sulfate gave 4-(2-chloromethyl) phenyl ether hydrochloride. Finally, it is reacted with an appropriate amount of 1-amine to give the target product 1-{2-[4-(Chloromethyl) phenol] ethyl}azepane hydrochloride (1:1).
Safety Information:
- 1-{2-[4-(chlorine) phenol] ethyl}azepane hydrochloride (1:1) shall be used and operated in strict accordance with relevant safety regulations, wear protective glasses and gloves when using.
-Specific toxicities and hazards need to be further evaluated and validated, and an adequate risk assessment is required prior to use.
-During use, storage and handling, keep away from ignition and oxidizing agents, and avoid contact with skin and inhalation of dust or vapors.
-Follow local laws, regulations and safe operation guidelines when using and disposing.
Nature:
-Appearance: White crystal or crystalline powder.
-Solubility: Soluble in water and some organic solvents, such as ethanol and dimethyl sulfoxide.
-Melting Point: about 110-113 ℃.
Use:
-Drug synthesis: 1-{2-[4-(Chloromethyl) phenyl] ethyl}azepane hydrochloride (1:1) is a compound intermediate, commonly used in the preparation of drugs and bioactive molecules.
-Chemical research: The compound can be used in organic synthesis reactions, such as etherification reactions and alkylation reactions.
Method:
A preparation method is to react 4-(2-chloromethyl) phenol with azepane ring under the catalysis of linear sulfuric acid to generate 4-(2-sulfoxyethoxy) benzyl-2-chlorotoluene and subsequent acidification with sulfate gave 4-(2-chloromethyl) phenyl ether hydrochloride. Finally, it is reacted with an appropriate amount of 1-amine to give the target product 1-{2-[4-(Chloromethyl) phenol] ethyl}azepane hydrochloride (1:1).
Safety Information:
- 1-{2-[4-(chlorine) phenol] ethyl}azepane hydrochloride (1:1) shall be used and operated in strict accordance with relevant safety regulations, wear protective glasses and gloves when using.
-Specific toxicities and hazards need to be further evaluated and validated, and an adequate risk assessment is required prior to use.
-During use, storage and handling, keep away from ignition and oxidizing agents, and avoid contact with skin and inhalation of dust or vapors.
-Follow local laws, regulations and safe operation guidelines when using and disposing.
Last Update：2024-04-09 21:00:56
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Product Name: Bazedoxifene Impurity 10 Visit Supplier Webpage Request for quotationCAS: 223251-25-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 1H-Azepine, 1-[2-[4-(chloromethyl)phenoxy]ethyl]hexahydro-, hydrochloride (1:1) Visit Supplier Webpage Request for quotation
CAS: 223251-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 223251-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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